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What side effects may I notice from Synthroid?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • difficulty breathing, wheezing, or shortness of breath
  • chest pain
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  • nervousness
  • skin rash or hives
  • swelling of ankles, feet, or legs
  • tremors

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • changes in appetite
  • changes in menstrual periods
  • diarrhea
  • hair loss
  • headache
  • trouble sleeping
  • weight loss

This list may not describe all possible side effects.

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